Quantifying bone structure, micro-architecture, and pathophysiology with MRI
نویسندگان
چکیده
منابع مشابه
Characterization of Trabecular Bone Micro-Architecture in the Knee in Osteoarthrosis Using High-Resolution MRI
Osteoarthrosis (OA) is a multi-factorial disease characterized by the progressive loss of articular cartilage and the development subchondral sclerosis, intra-osseous cysts and osteophytes. In addition to changes in cartilage which occur in OA, it is suggested that early changes are seen in the adjoining subchondral and trabecular bone (1). In this work we develop, optimize and extend MR techni...
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Bone strength, which is resistance to fracture, depends not only on the bone mass, but also on its spatial distribution (microand macroarchitecture) and the intrinsic properties of the materials that constitute the bone [1]. A particular feature of the bone is the ability to adapt its size and shape in response to mechanical loads, through the process of modeling achieved by the independent act...
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The aim of this study is to evaluate, in vivo, trabecular bone structure of the calcaneus of healthy volunteers and osteoporotic patients by texture analysis of MR images. Automated methods of texture analysis cover a wide range of techniques enabling quantitative analysis of grey level intensity and distribution within a region of interest (ROI). Texture analysis is not used very frequently si...
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Micro-computed tomography (micro-CT) is an emerging technique for the nondestructive assessment and analysis of the three-dimensional trabecular bone structure. Trabecular bone consists of a complicated three-dimensional network of plates and rods, arranged in a lattice-like network [1]. Aging, disease process, and therapeutic agents could influence the number of elements in this network, their...
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Besides the overall mass density, strength of trabecular bone depends significantly on its microstructure. However, due to dose constraints in medical CT imaging, it is impossible to gain sufficient information about very fine bone structures in vivo on the micrometer scale. Here we show that a recently developed method of X-ray vector radiography (XVR), an imaging method which uses X-ray scatt...
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ژورنال
عنوان ژورنال: Clinical Radiology
سال: 2018
ISSN: 0009-9260
DOI: 10.1016/j.crad.2017.12.010